Symptoms of Covid Differ by Vaccination Status: ZOE Health Study

Covid infections come with dozens of different potential symptoms, ranging from mild fatigue to weird like “Covid tongue”.

Which ones will you personally experience if you get infected soon? It depends on your vaccination status, suggests the ZOE Health Study, a joint project between the health science society ZOE and researchers from King’s College London, Massachusetts General Hospital, Harvard and Stanford University.

The project recently shared an updated list of the main symptoms of Covid reported by the more than 4 million users of the ZOE Covid Study app, which since 2020 tracks the symptoms of the virus based on data entered daily by users.

Here are the most commonly reported symptoms of Covid among three vaccination groups – people who have completed their primary series, people with a two-dose vaccine, and those who are not vaccinated – ranked by how often they were reported.

Common symptoms of Covid-19 based on vaccination status

Ranked based on prevalence among ZOE Health Study app users

They completed their primary vaccination series

1. Sore throat

4. Persistent cough

2. Rhinorrhea

5. Headache

Have a single dose of Covid vaccine

2. Rhinorrhea

5. Persistent cough

2. Sore throat

5. Persistent cough

Four of the five most commonly reported symptoms, including sore throat, runny nose, persistent cough, and headache, appeared in all three groups, but their prevalence varied. Unvaccinated people most commonly experienced fevers, which did not appear in the first five symptoms of the other groups.

But your vaccination status could affect how many of these symptoms occur at the same time. People who completed their primary series or received a dose of the vaccine reported fewer symptoms in a “shorter period of time” than unvaccinated people, the study says.

In a 2021 study by the Centers for Disease Control and Prevention, participants with one or two doses of the Covid vaccine had an approximately 60 percent lower risk of developing symptoms such as fever than unvaccinated people. According to the study, vaccinated participants spent an average of two to six fewer sick days in bed than those who were not vaccinated.

The ZOE study pointed to a finding common to all three groups: a noticeable decline in ‘traditional’ Covid symptoms from the initial strain of the virus, such as shortness of breath and loss of smell.

Shortness of breath ranked as the 29th most common symptom among those who completed the primary series and the 30th among those who are not vaccinated.

Omicron may have something to do with this: Other research has found that the newer variant is less likely than previous Covid strains to cause symptoms such as a loss of taste or smell.

The ZOE study did not take into account which Covid variant caused the infections, how many infections were the first Covid experiences, whether a user received booster doses, patient demographics information, and the severity of people’s symptoms.

The inclusion of booster dose data could potentially change the study’s symptom list and their potential duration for people who have completed the primary vaccine series.

Protection from the last dose of the vaccine decreases significantly over time, meaning that some people in that study category may be well protected while others may be closer to those who are only partially vaccinated or not at all. vaccinated.

Your most effective virus protection now includes a new omcron-specific booster shot. It is more effective against today’s Covid strains than the original vaccines, and early data suggests it will boost your protective antibodies ahead of an impending wave of the virus this winter.

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