One in 500 men can carry an extra sex chromosome (most unknowingly)

A new study suggests that up to one in 500 men may carry an extra sex chromosome – an X or a Y – but very few of them probably know.

The research, published June 9 in the journal Genetics in medicine (opens in a new tab), included data from over 207,000 men who provided information to the UK Biobank, a repository of genetic and health data of half a million UK-based participants. Typically, males carry an X-shaped and a Y-shaped sex chromosome in each of their cells, but among the study participants were 213 men who carried an extra X chromosome and 143 who had an extra Y chromosome.

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